Our Approach to Custom CRISPR Solutions
In order to develop the best custom CRISPR solution for every unique application, we perform mining of novel naturally occurring Cas nucleases in various metagenomic databases. If natural variants do not provide the desired result, we apply rational design and directed evolution methods to deliver world-class CRISPR solutions to our partners.
Bioinformatics and AI
Our research workflow begins with bioinformatic analysis, during which we:
- Mine numerous databases
- Perform in silico protein activity predictions
- Conduct structural protein analysis
Discovery
Utilizing our bioinformatics capabilities, we identify novel naturally occurring proteins with unique characteristics:
- Size diversity for multiple delivery methods
- PAM diversity for expanded targeting of CRISPR-Cas capabilities
- Thermostability for applications in different thermal conditions
Development
Our research workflow begins with bioinformatic analysis, during which we:
- Increase cellular activity
- Enhance nuclease specificity
Verification
We ensure the precision and effectiveness of editing processes across different biological contexts by having capabilities to verify and optimize editing efficiency by delivering nucleases in a form of:
- RNP complex
- mRNA
- DNA
Partner With Us
Contact us and learn how our technology can be applied in your activities.
Reach out to discuss how we can work together.