Nuclease Expertise
As one of the pioneers of CRISPR-Cas technology, we have gained deep knowledge and expertise in the field. We leverage our experience to enable other companies with optimizing expression and purification of their nucleases, as well as performing their biochemical analysis, using our extended assay portfolio.
Protein screening
We specialize in Cas nuclease characterization through various screening assays:
TXTL or cell lysates assay:
- dsDNA cleavage
- PAM determination
- Collateral activity
- RNase activity
Expression in E. coli:
- RNA seq
Protein purification
We have extensive experience in protein purification, offering expertise in:
- Protein expression optimization
- Protein purification optimization
- Research grade protein preps
- Analytical size exclusion chromatography
Protein biochemical analysis
Our protein biochemical analysis capabilities include:
Activity evaluation assays:
- dsDNase/ RNase activity
- RNase activity
- Collateral activity
Stability/ NanoDSF assay
DNA and RNA binging assays
Why choose us?
Experience
More than 15 years of experience in the CRISPR field.
Quality
Scientific excellence recognized in top academic journals.
Efficiency
Dedicated team committed to meeting your project milestones.
Collaboration
Collaborative partner here to support you at all steps.
Partner With Us
Contact us and learn how our technology can be applied in your activities.
Reach out to discuss how we can work together.